THREE-DIMENSIONAL MODELS AS A NEW FRONTIER FOR STUDYING THE ROLE OF PROTEOGLYCANS IN THE NORMAL AND MALIGNANT BREAST MICROENVIRONMENT

Three-Dimensional Models as a New Frontier for Studying the Role of Proteoglycans in the Normal and Malignant Breast Microenvironment

The extracellular matrix (ECM) provides cues to direct mammogenesis, tumourigenesis and metastatic processes.Over the past several decades, two-dimensional (2D) culture models have been invaluable in furthering our understanding of the tumor microenvironment (TME), however, they still do not accurately emulate the associated biological complexities

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Dark Matter from freeze-in and its inhomogeneities

Abstract We consider generic freeze-in Door Seal processes for generation of Dark Matter, together with the consequent re-thermalization of the Standard Model fluid.We find that Dark Matter inherits the Standard Model adiabatic inhomogeneities on the cosmological scales probed by current observations, that were Toddler super-horizon during freeze-i

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Rural-urban comparisons of dengue seroprevalence in Malaysia

Abstract Background Each year an estimated 390 million dengue infections occur worldwide.In Malaysia, dengue is a growing public health concern but Hair Spray estimate of its disease burden remains uncertain.We compared the urban-rural difference of dengue seroprevalence and determined age-specific dengue seroprevalence in Malaysia.Methods We under

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Pars plana vitrectomy combined with internal limiting membrane peeling for recurrent macular edema due to branch retinal vein occlusion after antivascular endothelial growth factor treatments

Yukari Shirakata,1 Kouki Fukuda,1 Tomoyoshi Fujita,1 Yuki Nakano,1 Hiroyuki Nomoto,2 Hidetaka Yamaji,3 Fumio Shiraga,4 Akitaka Tsujikawa1 1Department of Ophthalmology, Faculty of Medicine, Kagawa University, Miki-cho, 2Nomoto Hair Spray Eye Clinic, Himeji, 3Department of Ophthalmology, Shirai Eye Hospital, Mitoyo, 4Department of Ophthalmology, Okay

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